2. Cell Cycle/DNA Damage Epigenetics
  3. Sirtuin
  4. SIRT3 activator 1

SIRT3 activator 1 (Compound 5v) is a SIRT3 activator. SIRT3 activator 1 selectively elevates SIRT3 expression, leading to the upregulation of SOD2 and OPA1 expression, effectively preventing mitochondrial dysfunction, mitigating oxidative stress, and preserving cardiomyocyte viability. SIRT3 activator 1 can be used for research of cardiovascular diseases.

For research use only. We do not sell to patients.

SIRT3 activator 1 Chemical Structure

SIRT3 activator 1 Chemical Structure

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SIRT3 activator 1 Related Antibodies

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Description

SIRT3 activator 1 (Compound 5v) is a SIRT3 activator. SIRT3 activator 1 selectively elevates SIRT3 expression, leading to the upregulation of SOD2 and OPA1 expression, effectively preventing mitochondrial dysfunction, mitigating oxidative stress, and preserving cardiomyocyte viability. SIRT3 activator 1 can be used for research of cardiovascular diseases[1].

In Vitro

SIRT3 activator 1 (0-10 μM) protects cardiomyocytes against oxidative damage induced by Doxorubicin (HY-15142A) in H9c2 cells by activating the SIRT3/SOD2 and OPA1 pathways[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SIRT3 activator 1 Related Antibodies
Molecular Weight

556.67

Formula

C32H41N2NaO5
SMILES

C[C@@]12[C@@]([H])([C@@](C)(CCC2)C(N3CCN(CC3)C(C4=CC=CC=C4C(O[Na])=O)=O)=O)CC[C@]5([C@]1(CC[C@]6(C5)C)[H])CC6=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SIRT3 activator 1 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SIRT3 activator 1Sirtuinmitochondrial dysfunctionoxidative stresscardiomyocyteInhibitorinhibitorinhibit

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