2. PROTAC
  3. PROTAC Linkers
  4. Sulfo DBCO-PEG4-Maleimide TEA

Sulfo DBCO-PEG4-Maleimide TEA 

Cat. No.: HY-140307A Purity: ≥95.0%
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Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Sulfo DBCO-PEG4-Maleimide TEA Chemical Structure

Sulfo DBCO-PEG4-Maleimide TEA Chemical Structure

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5 mg USD 150 In-stock
10 mg USD 250 In-stock
25 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

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Sulfo DBCO-PEG4-Maleimide TEA Related Antibodies

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Description

Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Molecular Weight

927.07

Formula

C45H62N6O13S
Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCC(NCC(S(=O)(O)=O)C(NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O)=O)=O)=O)=O.CCN(CC)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Sulfo DBCO-PEG4-Maleimide TEA Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfo DBCO-PEG4-MaleimidePROTAC LinkersPROTAClinkerubiquitin-proteasome systemdegradeInhibitorinhibitorinhibit

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