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SYNTi is a PDZ domain inhibitor targeting the syndecan/syntenin protein-protein Interaction. SYNTi exhibits an IC50 value of 400 nM and ligand efficiency (LE) value of 0.24. SYNTi can be used for breast cancer research.

For research use only. We do not sell to patients.

SYNTi Chemical Structure

SYNTi Chemical Structure

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SYNTi Related Antibodies

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Description

SYNTi is a PDZ domain inhibitor targeting the syndecan/syntenin protein-protein Interaction. SYNTi exhibits an IC50 value of 400 nM and ligand efficiency (LE) value of 0.24. SYNTi can be used for breast cancer research[1].

In Vitro

SYNTi (1-100 μM) significantly affects the migration speed and Euclidean distance of MDA-MB-231 cells[1].
SYNTi is not toxic at concentrations up to 100 μM in wild-type MDA-MB-231 breast carcinoma cells and in MDA-MB-231 cells with syntenin-KO[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SYNTi Related Antibodies
Molecular Weight

567.40

Formula

C28H24BrFN2O5
SMILES

O=C1N(CC2=CC(Br)=CC=C21)[C@H](C(N[C@H](C(O)=O)C)=O)CC3=CC=C(C=C3)C4=CC(C(C)=O)=CC=C4F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SYNTi Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SYNTiOthersMDA-MB-231MDA-MB-231 SyntKO cellsbreast cancerInhibitorinhibitorinhibit

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