Thiazole orange dimer YOYO 1 (Synonyms: YOYO 1; YOYO1)

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Thiazole orange dimer YOYO 1 is a green fluorescent dye used for DNA staining. It belongs to the monomethine cyanine dye family and is a tetracationic homodimer of oxazole yellow (abbreviated as YO, hence the name YOYO), usually provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) has a very low fluorescence quantum yield, but after binding to double-stranded DNA through diintercalation, the fluorescence intensity is increased by 3200 times (λmax 489 nm; λmax 509 nm).

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Thiazole orange dimer YOYO 1 Chemical Structure

CAS No. : 143413-85-8

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Description	Thiazole orange dimer YOYO 1 is a green fluorescent dye used for DNA staining. It belongs to the monomethine cyanine dye family and is a tetracationic homodimer of oxazole yellow (abbreviated as YO, hence the name YOYO), usually provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) has a very low fluorescence quantum yield, but after binding to double-stranded DNA through diintercalation, the fluorescence intensity is increased by 3200 times (λmax 489 nm; λmax 509 nm).
Molecular Weight	1270.64
Formula	C₄₉H₅₈I₄N₆O₂
CAS No.	143413-85-8
SMILES	CN1C2=CC=CC=C2O/C1=C\C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](CCC[N+](CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=C(O/7)C=CC=C8)C)(C)C)(C)C.[I-].[I-].[I-].[I-]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (264 KB) Handling Instructions (2659 KB)
References	[1]. Wang L, et al.Ultrafast Transient Absorption Spectra of Photoexcited YOYO-1 molecules call for additional investigations of their fluorescence quenching mechanism. J Photochem Photobiol A Chem. 2018 Dec 1;367:411-419.

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Thiazole orange dimer YOYO 1 (Synonyms: YOYO 1; YOYO1)

Thiazole orange dimer YOYO 1 Related Antibodies

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