1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 10-Formyltetrahydrofolic acid

10-Formyltetrahydrofolic acid is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (10-Formyltetrahydrofolic acid disodium) usually boasts enhanced water solubility and stability.

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10-Formyltetrahydrofolic acid Chemical Structure

10-Formyltetrahydrofolic acid Chemical Structure

CAS No. : 2800-34-2

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Description

10-Formyltetrahydrofolic acid is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines[1].

In Vivo

10-Formyltetrahydrofolic acid in the liver of male Sprague-Dawley rats increases significantly after 30 and 60 minutes by administration of 1.3 mmol/kg methionine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

473.44

Formula

C20H23N7O7

CAS No.
SMILES

O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2NC3=C(N=C(N)NC3=O)NC2)C=O)C=C1)=O

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
10-Formyltetrahydrofolic acid
Cat. No.:
HY-112169
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