2. Others
  3. Isotope-Labeled Compounds
  4. 15-Keto Bimatoprost-d5

15-Keto Bimatoprost-d5 is the deuterium labeled 15-Keto Bimatoprost. 15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive[1][2].

For research use only. We do not sell to patients.

15-Keto Bimatoprost-d<sub>5</sub> Chemical Structure

15-Keto Bimatoprost-d5 Chemical Structure

Size Price Stock Quantity
1 mg USD 2380 In-stock
5 mg USD 7100 In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 15-Keto Bimatoprost-d5:

15-Keto Bimatoprost-d5 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

15-Keto Bimatoprost-d5 is the deuterium labeled 15-Keto Bimatoprost. 15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

15-Keto Bimatoprost-d5 Related Antibodies
Molecular Weight

418.58

Formula

C25H30D5NO4
Unlabeled CAS

1163135-96-3
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC([2H])([2H])C([2H])([2H])[2H])CCC/C=C\C[C@@H]1[C@@H](/C=C/C(CCC2=CC=CC=C2)=O)[C@H](O)C[C@@H]1O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : ≥ 10 mg/mL (23.89 mM)

DMF : ≥ 2.5 mg/mL (5.97 mM)

DMSO : ≥ 2 mg/mL (4.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

PBS (pH 7.2) : ≥ 0.5 mg/mL (1.19 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3890 mL 11.9451 mL 23.8903 mL
5 mM 0.4778 mL 2.3890 mL 4.7781 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
PBS (pH 7.2) / DMSO / DMF / Ethanol 1 mM 2.3890 mL 11.9451 mL 23.8903 mL 59.7257 mL
DMF / Ethanol 5 mM 0.4778 mL 2.3890 mL 4.7781 mL 11.9451 mL
Ethanol 10 mM 0.2389 mL 1.1945 mL 2.3890 mL 5.9726 mL
15 mM 0.1593 mL 0.7963 mL 1.5927 mL 3.9817 mL
20 mM 0.1195 mL 0.5973 mL 1.1945 mL 2.9863 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

15-Keto Bimatoprost-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

15-Keto Bimatoprost-d5Isotope-Labeled CompoundsInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
15-Keto Bimatoprost-d5
Cat. No.:
HY-132277S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.