2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3-Methoxy-4-hydroxyphenylglycol

3-Methoxy-4-hydroxyphenylglycol  (Synonyms: HMPG; MHPG; MOPEG)

Cat. No.: HY-113323 Purity: 97.85%
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3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc.

For research use only. We do not sell to patients.

3-Methoxy-4-hydroxyphenylglycol Chemical Structure

3-Methoxy-4-hydroxyphenylglycol Chemical Structure

CAS No. : 534-82-7

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1 mg USD 80 In-stock
5 mg USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 3-Methoxy-4-hydroxyphenylglycol:

3-Methoxy-4-hydroxyphenylglycol Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 3-Methoxy-4-hydroxyphenylglycol

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Description

3-Methoxy-4-hydroxyphenylglycol (HMPG) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol can be used for research of depression, chronic schizophrenia, etc[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

184.19

Formula

C9H12O4
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

OC(C1=CC=C(O)C(OC)=C1)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (542.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4292 mL 27.1459 mL 54.2918 mL
5 mM 1.0858 mL 5.4292 mL 10.8584 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.07%

COA (247 KB) LCMS (88 KB) Elemental Analysis Report (105 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.4292 mL 27.1459 mL 54.2918 mL 135.7294 mL
5 mM 1.0858 mL 5.4292 mL 10.8584 mL 27.1459 mL
10 mM 0.5429 mL 2.7146 mL 5.4292 mL 13.5729 mL
15 mM 0.3619 mL 1.8097 mL 3.6195 mL 9.0486 mL
20 mM 0.2715 mL 1.3573 mL 2.7146 mL 6.7865 mL
25 mM 0.2172 mL 1.0858 mL 2.1717 mL 5.4292 mL
30 mM 0.1810 mL 0.9049 mL 1.8097 mL 4.5243 mL
40 mM 0.1357 mL 0.6786 mL 1.3573 mL 3.3932 mL
50 mM 0.1086 mL 0.5429 mL 1.0858 mL 2.7146 mL
60 mM 0.0905 mL 0.4524 mL 0.9049 mL 2.2622 mL
80 mM 0.0679 mL 0.3393 mL 0.6786 mL 1.6966 mL
100 mM 0.0543 mL 0.2715 mL 0.5429 mL 1.3573 mL
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3-Methoxy-4-hydroxyphenylglycol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Methoxy-4-hydroxyphenylglycol534-82-7HMPG MHPG MOPEGEndogenous Metabolitedepressionnoradrenergicnorepinephrinechronic schizophreniaInhibitorinhibitorinhibit

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