3-Methylbutyryl-DL-carnitine-d₉ hydrochloride

Name: 3-Methylbutyryl-DL-carnitine-d 9 hydrochloride
Brand: MedChemExpress
SKU: HY-132959S
Rating: 4.5 (1 reviews)

Cat. No.: HY-132959S Purity: 99.72%: FAQs
Data Sheet SDS COA Handling Instructions

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3-Methylbutyryl-DL-carnitine-d₉ (hydrochloride) is the deuterium labeled 3-Methylbutyryl-DL-carnitine hydrochloride[1].

For research use only. We do not sell to patients.

3-Methylbutyryl-DL-carnitine-d<sub>9</sub> hydrochloride Chemical Structure

3-Methylbutyryl-DL-carnitine-d₉ hydrochloride Chemical Structure

CAS No. : 2608872-54-2

Size	Price	Stock	Quantity
1 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 480	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

3-Methylbutyryl-DL-carnitine-d₉ (hydrochloride) is the deuterium labeled 3-Methylbutyryl-DL-carnitine hydrochloride[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

290.83

Formula

C₁₂H₁₅D₉ClNO₄

CAS No.

2608872-54-2

Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([N+](C([2H])([2H])[2H])(CC(CC(O)=O)OC(CC(C)C)=O)C([2H])([2H])[2H])([2H])[2H].[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

Ethanol : ≥ 25 mg/mL (85.96 mM)

DMSO : ≥ 20 mg/mL (68.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 15 mg/mL (51.58 mM)

PBS (pH 7.2) : ≥ 10 mg/mL (34.38 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4384 mL	17.1922 mL	34.3843 mL
5 mM	0.6877 mL	3.4384 mL	6.8769 mL
10 mM	0.3438 mL	1.7192 mL	3.4384 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.72%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (256 KB) HNMR (496 KB) RP-HPLC (501 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

PBS (pH 7.2) / DMF / DMSO / Ethanol	1 mM	3.4384 mL	17.1922 mL	34.3843 mL	85.9609 mL
	5 mM	0.6877 mL	3.4384 mL	6.8769 mL	17.1922 mL
	10 mM	0.3438 mL	1.7192 mL	3.4384 mL	8.5961 mL
	15 mM	0.2292 mL	1.1461 mL	2.2923 mL	5.7307 mL
	20 mM	0.1719 mL	0.8596 mL	1.7192 mL	4.2980 mL
	25 mM	0.1375 mL	0.6877 mL	1.3754 mL	3.4384 mL
	30 mM	0.1146 mL	0.5731 mL	1.1461 mL	2.8654 mL
DMF / DMSO / Ethanol	40 mM	0.0860 mL	0.4298 mL	0.8596 mL	2.1490 mL
DMF / DMSO / Ethanol	50 mM	0.0688 mL	0.3438 mL	0.6877 mL	1.7192 mL
DMSO / Ethanol	60 mM	0.0573 mL	0.2865 mL	0.5731 mL	1.4327 mL
Ethanol	80 mM	0.0430 mL	0.2149 mL	0.4298 mL	1.0745 mL