Search Result
Results for "
5,8,11,14-Eicosatetraenamide,_N-_2-hydroxyethyl_-,__5Z,8Z,11Z,14Z_-
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-113463
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- HY-146919S
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- HY-121995
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Others
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Others
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(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges .
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- HY-113029
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- HY-W718405
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Others
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Others
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(5Z,14Z)-5,14-Eicosadienoic acid is a ω-6 C20:2 fatty acid .
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- HY-E70269
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- HY-149589
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Leukotriene Receptor
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Inflammation/Immunology
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11(Z),14(Z)-Eicosadienoic acid is a unsaturated fattly acid that inhibits [ 3H] leukotriene B4 (LTB4) binding to pig neutrophil membranes with a Ki of 3 μM. 11(Z),14(Z)-Eicosadienoic acid has inflammatory activities .
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- HY-120500
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- HY-108398B
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Endogenous Metabolite
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Metabolic Disease
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11(Z),14(Z),17(Z)-Eicosatrienoic acid is an unsaturated fatty acid that can maintain the continued replication of functional mitochondria in Saccharomyces cerevisiae (KD115) .
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- HY-W127486
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Biochemical Assay Reagents
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Others
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N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B0914
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- HY-W012723
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Biochemical Assay Reagents
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Others
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2-Hydroxyethyl methacrylate (HEMA) is a monomer used in the synthesis of various polymers, and the polymer PHEMA of 2-Hydroxyethyl methacrylate is widely used in the synthesis of dental composite materials .
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- HY-113102B
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Endogenous Metabolite
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Cancer
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9(Z),11(Z)-octadecadienoic acid is an isomer of linoleic acid and has antitumor activity (EC 50 = 446.1 µM) .
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- HY-140125
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ADC Linker
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Cancer
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2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-132313S
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- HY-118213
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Fluorescent Dye
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Others
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N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
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- HY-W042853
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- HY-W585980S
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Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4
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Isotope-Labeled Compounds
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Others
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Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4 (Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4) is a deuterium labeled compound.
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- HY-B2221B
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hydroxyethyl pectin glycosidase
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Biochemical Assay Reagents
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Others
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Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
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- HY-140126
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ADC Linker
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Cancer
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Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-112531
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-112531A
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-W145519
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Biochemical Assay Reagents
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Others
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Hydroxyethyl starch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-156513
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ADC Cytotoxin
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Cancer
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7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a Camptothecin (HY-16560) analogue. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a ADC cytotoxin that can be used for synthesis of ADCs, and for cancer research .
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- HY-143790S
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- HY-W127642
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Bis(2-hydroxyethyl)dimethylaminium chloride
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Biochemical Assay Reagents
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Others
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Bis(2-hydroxyethyl)dimethylammonium Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W127783
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- HY-N10365
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Others
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Neurological Disease
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6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, a alkaloid, significantly perturbates the features of cellular organelles including early endosomes, mitochondria and autophagosomes (Parkinson’s Disease patient-derived olfactory cells) .
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- HY-N10358
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NF-κB
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Others
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3-(2-Hydroxyethyl) thio withaferin A is a Withaferin A derivative. Withaferin A, a steroidal lactone, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding .
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- HY-20797S
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- HY-154161
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-41939
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Biochemical Assay Reagents
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Others
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1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-132805S
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Isotope-Labeled Compounds
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Others
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N-Acetyl-S-(2-hydroxyethyl)-L-cysteine-d4 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(2-hydroxyethyl)-L-cysteine dicyclohexylamine salt[1].
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- HY-152790
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Nucleoside Antimetabolite/Analog
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Others
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5-(2-Hydroxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
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- HY-W092298S
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- HY-154699
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-138094
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Drug Metabolite
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Infection
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N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
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- HY-W440816
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Liposome
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Others
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Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid that can be used for compound synthesis .
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- HY-154160
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-B1209
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7-(β-hydroxyethyl)theophylline
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Others
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Cardiovascular Disease
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Etofylline (7-(β-Hydroxyethyl)theophylline) is a N-7-substituted derivative of Theophylline. Etofylline is a bronchodilator which can be used for the research of asthma. Etofylline is also an anticholesteremic and reduces total cholesterol level in the blood .
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- HY-W006957
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Nucleoside Antimetabolite/Analog
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Cancer
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N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-W127365
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Biochemical Assay Reagents
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Others
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Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium (acetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-147018
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Liposome
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Others
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1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery .
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- HY-152324
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Nucleoside Antimetabolite/Analog
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Cancer
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2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-P3124A
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Somatostatin Receptor
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Cancer
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BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
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- HY-P3124
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Somatostatin Receptor
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Cancer
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BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
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- HY-148363
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Liposome
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Inflammation/Immunology
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Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
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- HY-119648A
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CD38
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Inflammation/Immunology
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(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ .
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- HY-117016
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(7Z,11Z)-Nonacosadiene
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Others
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Others
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Nonacosadiene is the pheromone of Drosophila melanogaster from a tetrahydrophyridine derivative .
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- HY-D1551
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Fluorescent Dye
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Others
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10-(4-(Bis(2-hydroxyethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide, a BODIPY derivative, is a fluorescent indicator for detecting Pb 2+ (Ex=504 nM, Em=510 nM) .
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- HY-W012728
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Biochemical Assay Reagents
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Others
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2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-139421
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Others
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Cardiovascular Disease
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(Z)-16-(Ethylcarbamoylamino)hexadec-11-enoic acid (Compound 21) is a vasorelaxant (EC50=5.7 μM) that can be used in cardiovascular disease research .
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- HY-W127668
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Biochemical Assay Reagents
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Others
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(2-hydroxyethyl)triethylammonium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-148100
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NOX-E36
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Others
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Inflammation/Immunology
Cancer
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Emapticap pegol is a inhibitor of pro-inflammatory chemokine C-C motif-ligand 2 (CCL2). Emapticap pegol is a 40-nucleotide oligonucleotide aptamer, displays different Spiegelmers (L-RNA aptamer) isform in human (NOX-E36) and mouse (mNOX-E36) .
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- HY-117422
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11-Oxo-prosta-5Z,12E,14Z-trien-1-oic acid
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PPAR
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Cancer
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CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes .
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- HY-125734
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Liposome
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Others
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DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
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- HY-A0144
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Adrenergic Receptor
AMPK
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Cardiovascular Disease
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Etilefrine (3-[2-(ethylamino)-1-hydroxyethyl]phenol) is an α adrenergic agonist . Etilefrine also is an AMPK activator . Etilefrine can be used for the research of postural hypotension .
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- HY-P4154
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ALM-488
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Fluorescent Dye
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Neurological Disease
|
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
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- HY-P1103A
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CXCR
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Cancer
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CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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- HY-P1103
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CXCR
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Cancer
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CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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- HY-79513
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tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
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Amino Acid Derivatives
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Others
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(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
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-
- HY-W127824
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(5Z,9Z,14Z)-5,10,15-Tris(4-nitrophenyl)-22,24-dihydro-21H-corri
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Biochemical Assay Reagents
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Others
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5,10,15-tris(4-nitrophenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
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-
- HY-P2231A
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MEDI0382 acetate
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GCGR
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Metabolic Disease
|
Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
|
-
- HY-P2231
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MEDI0382
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GCGR
|
Metabolic Disease
|
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
|
-
- HY-15738
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GNF-5
3 Publications Verification
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Bcr-Abl
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Cancer
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GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 µM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer .
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-
- HY-P3066
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d(CH2)5Tyr(Et)VAVP
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Vasopressin Receptor
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Metabolic Disease
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
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-
- HY-P1321
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1229U91; GW1229
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Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
|
-
- HY-P1321A
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1229U91 TFA; GW1229 TFA
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-118213
-
|
Fluorescent Dyes/Probes
|
N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
|
Cat. No. |
Product Name |
Type |
-
- HY-W145519
-
|
Biochemical Assay Reagents
|
Hydroxyethyl starch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-41939
-
|
Biochemical Assay Reagents
|
1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127486
-
|
Biochemical Assay Reagents
|
N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-153124
-
-
- HY-W127642
-
Bis(2-hydroxyethyl)dimethylaminium chloride
|
Biochemical Assay Reagents
|
Bis(2-hydroxyethyl)dimethylammonium Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W440816
-
|
Drug Delivery
|
Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid that can be used for compound synthesis .
|
-
- HY-W127365
-
|
Biochemical Assay Reagents
|
Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium (acetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-147018
-
|
Drug Delivery
|
1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery .
|
-
- HY-148363
-
|
Drug Delivery
|
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
|
-
- HY-W012728
-
|
Biochemical Assay Reagents
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127668
-
|
Biochemical Assay Reagents
|
(2-hydroxyethyl)triethylammonium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127824
-
(5Z,9Z,14Z)-5,10,15-Tris(4-nitrophenyl)-22,24-dihydro-21H-corri
|
Biochemical Assay Reagents
|
5,10,15-tris(4-nitrophenyl)corrole is a corrole derivative used as a trianionic ligand for transition metals.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W127783
-
-
- HY-P3124A
-
|
Somatostatin Receptor
|
Cancer
|
BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
|
-
- HY-P4761
-
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Peptides
|
Others
|
N-2-Hydroxyethyl-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P3124
-
|
Somatostatin Receptor
|
Cancer
|
BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
|
-
- HY-P4756
-
|
Peptides
|
Others
|
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P4755
-
|
Peptides
|
Others
|
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-158104
-
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Peptides
|
Others
|
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
|
-
- HY-P4154
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ALM-488
|
Fluorescent Dye
|
Neurological Disease
|
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
|
-
- HY-P1103A
-
|
CXCR
|
Cancer
|
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
|
-
- HY-P1103
-
|
CXCR
|
Cancer
|
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
|
-
- HY-79513
-
tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
|
Amino Acid Derivatives
|
Others
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
|
-
- HY-P2231A
-
MEDI0382 acetate
|
GCGR
|
Metabolic Disease
|
Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
|
-
- HY-P2231
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MEDI0382
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GCGR
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Metabolic Disease
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Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
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- HY-P3066
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d(CH2)5Tyr(Et)VAVP
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Vasopressin Receptor
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Metabolic Disease
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SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
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- HY-P4757
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Peptides
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Others
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N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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-
- HY-P10026
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LY-3457263
|
Peptides
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Metabolic Disease
|
Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity .
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- HY-P1321
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1229U91; GW1229
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Neuropeptide Y Receptor
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Neurological Disease
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GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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- HY-P1321A
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1229U91 TFA; GW1229 TFA
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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- HY-125357
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|
Peptides
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Metabolic Disease
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Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
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- HY-P10016
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HS-20039; EPO-018B
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Peptides
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Endocrinology
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Pegmolesatide(HS-20039; EPO-018B) a synthetic peptide-based erythropoiesis-stimulating agent, can be used for ??the study of anemia in chronic kidney disease .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-146919S
-
|
4E,14Z-Sphingadiene-d7 is deuterium labeled 4E,14Z-Sphingadiene.
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-
-
- HY-132313S
-
|
2-(1-Hydroxyethyl) promazine-d4 Sulfoxide is the deuterium labeled 2-(1-Hydroxyethyl) promazine-d4 Sulfox[1].
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-
-
- HY-W585980S
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|
Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4 (Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4) is a deuterium labeled compound.
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-
-
- HY-143790S
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N-2-(Hydroxyethyl)-L-valine-d4 is the deuterium labeled N-2-(Hydroxyethyl)-L-valine[1].
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-
-
- HY-20797S
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1-BOC-4-(2-Hydroxyethyl)piperazine-d4 is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine[1].
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-
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- HY-132805S
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N-Acetyl-S-(2-hydroxyethyl)-L-cysteine-d4 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(2-hydroxyethyl)-L-cysteine dicyclohexylamine salt[1].
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-
-
- HY-W092298S
-
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Methyl 4-(2-hydroxyethyl)benzoate- 13C6,d2 is 13C and deuterated labeled Methyl 4-(2-hydroxyethyl)benzoate (HY-W092298).
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