2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Banoxantrone-d12 dihydrochloride

Banoxantrone-d12 dihydrochloride  (Synonyms: AQ4N-d12 dihydrochloride)

Cat. No.: HY-13562AS Purity: 95.03%
COA Handling Instructions

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Banoxantrone-d12 (dihydrochloride) is the deuterium labeled Banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

For research use only. We do not sell to patients.

Banoxantrone-d<sub>12</sub> dihydrochloride Chemical Structure

Banoxantrone-d12 dihydrochloride Chemical Structure

CAS No. : 1562066-98-1

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1 mg USD 320 In-stock
5 mg USD 980 In-stock
10 mg USD 1380 In-stock
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Based on 1 publication(s) in Google Scholar

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Banoxantrone-d12 dihydrochloride Related Antibodies

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Description

Banoxantrone-d12 (dihydrochloride) is the deuterium labeled Banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.

Molecular Weight

529.48

Formula

C22H18D12Cl2N4O6
CAS No.
Unlabeled CAS

252979-56-9
Appearance

Solid

Color

White to blue

SMILES

O=N(C([2H])([2H])[2H])(C([2H])([2H])[2H])CCNC1=CC=C(NCCN(C([2H])([2H])[2H])(C([2H])([2H])[2H])=O)C(C(C2=C(O)C=CC(O)=C23)=O)=C1C3=O.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (47.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8886 mL 9.4432 mL 18.8865 mL
5 mM 0.3777 mL 1.8886 mL 3.7773 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 95.03%

COA (258 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8886 mL 9.4432 mL 18.8865 mL 47.2161 mL
5 mM 0.3777 mL 1.8886 mL 3.7773 mL 9.4432 mL
10 mM 0.1889 mL 0.9443 mL 1.8886 mL 4.7216 mL
15 mM 0.1259 mL 0.6295 mL 1.2591 mL 3.1477 mL
20 mM 0.0944 mL 0.4722 mL 0.9443 mL 2.3608 mL
25 mM 0.0755 mL 0.3777 mL 0.7555 mL 1.8886 mL
30 mM 0.0630 mL 0.3148 mL 0.6295 mL 1.5739 mL
40 mM 0.0472 mL 0.2361 mL 0.4722 mL 1.1804 mL
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Banoxantrone-d12 dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Banoxantrone-d121562066-98-1AQ4N-d12TopoisomeraseInhibitorinhibitorinhibit

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