1. Metabolic Enzyme/Protease Anti-infection
  2. Fatty Acid Synthase (FASN) SARS-CoV
  3. FASN-IN-4

FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.

For research use only. We do not sell to patients.

FASN-IN-4 Chemical Structure

FASN-IN-4 Chemical Structure

CAS No. : 1375105-96-6

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Solution
10 mM * 1 mL in DMSO USD 599 Ask For Quote & Lead Time
Solid
2 mg USD 228 Ask For Quote & Lead Time

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Description

FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29)[1]. FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM[2].

IC50 & Target

IC50: 10 nM (FASN)[1]
EC50: 18.6 nM (SARS-CoV-2)[2]

In Vitro

The FASN inhibitor, FASN-IN-4 inhibits SARS-CoV-2 replication, and has the potential for COVID-19 research[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

477.58

Formula

C26H27N3O4S

CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O=C1COC2(CCN(S(=O)(C3=CC=C(C4=CC=C5C=CC=NC5=C4)C=C3)=O)CC2)CN1C6CC6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FASN-IN-4
Cat. No.:
HY-12648
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