Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (5662):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-Y0479AS

L-Lactic acid-¹³C₃ sodium		≥98.0%
L-Lactic acid-¹³C₃ (sodium) is the ¹³C labeled L-Lactic acid. L-Lactic acid-¹³C₃ sodium can be used for lactate metabolism research[1].

HY-I1124

L-Valine-d₈		99.10%
L-Valine-d₈ is a deuterated form of L-Valine. L-Valine-d₈ can be used in the labelled synthesis of L-valineamide-d8 intermediate[1]. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[2].

HY-Y0534S

Sodium cyanoboronhydride-d₃		98.03%
Sodium cyanoboronhydride-d₃ is the deuterium labeled Sodium cyanoboronhydride[1].

HY-18569S

3-Indoleacetic acid-d₅		99.84%
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-108872S

Water-¹⁸O		99.99%
Water-¹⁸O is the ¹⁸O-labeled Water[1].

HY-W017007SA

3-Methyl-L-histidine-d₃ hydrochloride
3-Methyl-L-histidine-d₃ hydrochloride is the deuterium labeled 3-Methyl-L-histidine hydrochloride. 3-Methyl-L-histidine hydrochloride can be found in actin and myosin and is a derivative of histidine.

HY-12678S1

Entrectinib-d₈		99.82%
Entrectinib-d8 (NMS-E628-d8; RXDX-101-d8) is a deuterated version of Entrectinib (HY-12678). Entrectinib (NMS-E628) is an orally available, blood-brain barrier permeable, central nervous system active TrkA/B/C, ROS1 and ALK inhibitor with IC₅₀ values of 1, 3, 5, 12 and 12, respectively. 7 nM. Entrectinib induces apoptosis and cycle arrest in cancer cells, has anti-tumor activity, and also alleviates bleomycin-induced pulmonary fibrosis in mice.

HY-10528S

Tasquinimod-d₃		99.34%
Tasquinimod-d3 (ABR-215050-d3) is the deuterium labeled Tasquinimod (HY-10528). Tasquinimod is an oral antiangiogenic agent, which plays an important role in castration-resistant prostate cancer. Tasquinimod binds to the regulatory Zn²⁺ binding domain of HDAC4 with K_d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor.

HY-100806S

Kynurenic acid-d₅		98.35%
Kynurenic acid-d₅ is the deuterium labeled Kynurenic acid. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8[1][2].

HY-B1342S4

Retinol-d₅
Retinol-d₅ is the deuterium labeled Retinol[1].

HY-Y0479S

L-Lactic acid-¹³C₃		99.10%
L-Lactic acid-¹³C₃ is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-¹³C₃ can be used for lactate metabolism research[1].

HY-N1446S1

Oleic acid-d₂		≥98.0%
Oleic acid-d₂) is the deuterium labeled Oleic acid. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2].

HY-N0473S

L-Tyrosine-d₄		≥98.0%
L-Tyrosine-d₄ is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].

HY-W050026S

Phenylacetylglutamine-d₅		98.01%
Phenylacetylglutamine-d₅ is the deuterium labeled Phenylacetylglutamine. Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation[1].

HY-132787S

N-Nitrosodiethanolamine-d₈		98.33%
N-Nitrosodiethanolamine-d₈ is the deuterium labeled N-Nitrosodiethanolamine[1].

HY-153939S

Idasanutlin-d₃-1		98.31%
Idasanutlin-d₃-1 (RG7388-d₃-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia.

HY-W014423S4

L-Histidine-d₅ hydrochloride hydrate		99.63%
L-Histidine-d₅ (hydrochloride hydrate) is the deuterium labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.

HY-Y0966S1

Glycine-d₂		≥99.0%
Glycine-d₂ is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

HY-B2227BS1

Lactate-d₃ sodium
Lactate-d₃ (sodium) is the deuterium labeled Lactate sodium. Lactate sodium is the product of glycogenolysis and glycolysis. Lactate sodium functions in a variety of biochemical processes[1][2].

HY-W017007S

3-Methyl-L-histidine-d₃
3-Methyl-L-histidine-d₃ is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is a biomarker for meat consumption, especially chicken. It is also a biomarker for the consumption of soy products.

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