2. Signaling Pathways
  3. Epigenetics
  4. SF3B1
  5. SF3B1 Degrader

SF3B1 Degrader

SF3B1 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-141881
    PROTAC-O4I2
    		Degrader 98.96%
    PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells.