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  4. Ac-pSar12-OH

Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC).

For research use only. We do not sell to patients.

Ac-pSar12-OH Chemical Structure

Ac-pSar12-OH Chemical Structure

CAS No. : 2313534-24-4

Size Price Stock Quantity
1 mg USD 56 In-stock
5 mg USD 140 In-stock
10 mg USD 220 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Ac-pSar12-OH Related Antibodies

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Description

Ac-pSar12-OH, as a linker, can be used for preparation of Ligand-Drug-Conjugate (LDC)[1][2].

Molecular Weight

912.99

Formula

C38H64N12O14
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O=C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(CN(C)C(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (109.53 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0953 mL 5.4765 mL 10.9530 mL
5 mM 0.2191 mL 1.0953 mL 2.1906 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.52%

COA (241 KB) RP-HPLC (277 KB) LCMS (118 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0953 mL 5.4765 mL 10.9530 mL 27.3826 mL
5 mM 0.2191 mL 1.0953 mL 2.1906 mL 5.4765 mL
10 mM 0.1095 mL 0.5477 mL 1.0953 mL 2.7383 mL
15 mM 0.0730 mL 0.3651 mL 0.7302 mL 1.8255 mL
20 mM 0.0548 mL 0.2738 mL 0.5477 mL 1.3691 mL
25 mM 0.0438 mL 0.2191 mL 0.4381 mL 1.0953 mL
30 mM 0.0365 mL 0.1826 mL 0.3651 mL 0.9128 mL
40 mM 0.0274 mL 0.1369 mL 0.2738 mL 0.6846 mL
50 mM 0.0219 mL 0.1095 mL 0.2191 mL 0.5477 mL
60 mM 0.0183 mL 0.0913 mL 0.1826 mL 0.4564 mL
80 mM 0.0137 mL 0.0685 mL 0.1369 mL 0.3423 mL
100 mM 0.0110 mL 0.0548 mL 0.1095 mL 0.2738 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Ac-pSar12-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-pSar12-OH2313534-24-4OtherslinkerLigand-Drug-Conjugate (LDC)Inhibitorinhibitorinhibit

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