2. Anti-infection Apoptosis
  3. Bacterial Antibiotic Apoptosis
  4. Actinomycin X2

Actinomycin X2  (Synonyms: Actinomycin V)

Cat. No.: HY-125747 Purity: ≥98.0%
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Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Actinomycin X2 Chemical Structure

Actinomycin X2 Chemical Structure

CAS No. : 18865-48-0

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Based on 1 publication(s) in Google Scholar

Actinomycin X2 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Actinomycin X2

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Description

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1][2].

In Vitro

Actinomycin X2 (1, 10 μM, 24 h) 通过 mTOR 途径联合 MiRNA144 诱导人前列腺癌细胞凋亡[2]。

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Actinomycin X2 Related Antibodies

Western Blot Analysis[2]

Cell Line: PC-3
Concentration: 1, 10 μM
Incubation Time: 24 h
Result: Inhibited the levels of mTOR, PI3K, and Akt.
Increased the level of PTEN.

Apoptosis Analysis[2]

Cell Line: PC-3
Concentration: 1, 10 μM
Incubation Time: 24, 48 h
Result: Increased the apoptotic rate.
Molecular Weight

1269.40

Formula

C62H84N12O17
CAS No.
Appearance

Solid

Color

Orange to red

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 12.7 mg/mL (10.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7878 mL 3.9389 mL 7.8777 mL
5 mM 0.1576 mL 0.7878 mL 1.5755 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (259 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7878 mL 3.9389 mL 7.8777 mL 19.6943 mL
5 mM 0.1576 mL 0.7878 mL 1.5755 mL 3.9389 mL
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Actinomycin X2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Actinomycin X218865-48-0Actinomycin VActinomycin X 2Actinomycin X-2BacterialAntibioticApoptosisMRSAPC-3Inhibitorinhibitorinhibit

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