1. Apoptosis Cell Cycle/DNA Damage Autophagy Metabolic Enzyme/Protease
  2. Apoptosis Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite
  3. Adenosine-13C5

Adenosine-13C5  (Synonyms: Adenine riboside-13C5; D-Adenosine-13C5)

Cat. No.: HY-B0228S1 Purity: 99.35%
COA Handling Instructions

Adenosine-13C5 is the 13C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].

For research use only. We do not sell to patients.

Adenosine-<sup>13</sup>C<sub>5</sub> Chemical Structure

Adenosine-13C5 Chemical Structure

CAS No. : 159496-13-6

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1 mg USD 370 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine-13C5:

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Description

Adenosine-13C5 is the 13C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

272.20

Formula

C513C5H13N5O4

CAS No.
Unlabeled CAS

58-61-7

Appearance

Solid

Color

White to off-white

SMILES

NC1=C(N=CN2[13C@H]3[13C@H](O)[13C@H](O)[13C@@H]([13CH2]O)O3)C2=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (122.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 6.67 mg/mL (24.50 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6738 mL 18.3688 mL 36.7377 mL
5 mM 0.7348 mL 3.6738 mL 7.3475 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.6738 mL 18.3688 mL 36.7377 mL 91.8442 mL
5 mM 0.7348 mL 3.6738 mL 7.3475 mL 18.3688 mL
10 mM 0.3674 mL 1.8369 mL 3.6738 mL 9.1844 mL
15 mM 0.2449 mL 1.2246 mL 2.4492 mL 6.1229 mL
20 mM 0.1837 mL 0.9184 mL 1.8369 mL 4.5922 mL
DMSO 25 mM 0.1470 mL 0.7348 mL 1.4695 mL 3.6738 mL
30 mM 0.1225 mL 0.6123 mL 1.2246 mL 3.0615 mL
40 mM 0.0918 mL 0.4592 mL 0.9184 mL 2.2961 mL
50 mM 0.0735 mL 0.3674 mL 0.7348 mL 1.8369 mL
60 mM 0.0612 mL 0.3061 mL 0.6123 mL 1.5307 mL
80 mM 0.0459 mL 0.2296 mL 0.4592 mL 1.1481 mL
100 mM 0.0367 mL 0.1837 mL 0.3674 mL 0.9184 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Adenosine-13C5
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