2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) 

Cat. No.: HY-P3561A Purity: 95.76%
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Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake.

For research use only. We do not sell to patients.

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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Chemical Structure

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA):

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Related Antibodies

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Description

Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake[1][2].

IC50 & Target

Melanocortin-4 receptor[2]
In Vivo

Agouti-related Protein (AGRP) (83-132) increases food intake and decreases spontaneous locomotor activity in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

5790.62 (free acid)

Formula

C235H362N76O67S11.xC2HF3O2
Unlabeled CAS

Appearance

Solid

Color

White to off-white

Sequence

Ser-Ser-Arg-Arg-Cys-Val-Arg-Leu-His-Glu-Ser-Cys-Leu-Gly-Gln-Gln-Val-Pro-Cys-Cys-Asp-Pro-Cys-Ala-Thr-Cys-Tyr-Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys-Tyr-Cys-Arg-Lys-Leu-Gly-Thr-Ala-Met-Asn-Pro-Cys-Ser-Arg-Thr-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
Sequence Shortening

SSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Purity & Documentation

Purity: 96.96%

COA (246 KB) RP-HPLC (114 KB) MS (195 KB)

Handling Instructions (2659 KB)
References
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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)Melanocortin ReceptorMC Receptorfood intakemelanocortin-4 receptorhypothalamusagouti-related proteinInhibitorinhibitorinhibit

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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)
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