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  4. ALS-I

ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain.

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ALS-I Chemical Structure

ALS-I Chemical Structure

CAS No. : 308818-13-5

Size Price Stock Quantity
5 mg USD 140 In-stock
10 mg USD 225 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain[1][2].

In Vivo

ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

416.55

Formula

C19H37NaO6S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=S(CCCOCC1OC(CCCCCCCCCCC)(C)OC1)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (300.08 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4007 mL 12.0034 mL 24.0067 mL
5 mM 0.4801 mL 2.4007 mL 4.8013 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4007 mL 12.0034 mL 24.0067 mL 60.0168 mL
5 mM 0.4801 mL 2.4007 mL 4.8013 mL 12.0034 mL
10 mM 0.2401 mL 1.2003 mL 2.4007 mL 6.0017 mL
15 mM 0.1600 mL 0.8002 mL 1.6004 mL 4.0011 mL
20 mM 0.1200 mL 0.6002 mL 1.2003 mL 3.0008 mL
25 mM 0.0960 mL 0.4801 mL 0.9603 mL 2.4007 mL
30 mM 0.0800 mL 0.4001 mL 0.8002 mL 2.0006 mL
40 mM 0.0600 mL 0.3001 mL 0.6002 mL 1.5004 mL
50 mM 0.0480 mL 0.2401 mL 0.4801 mL 1.2003 mL
60 mM 0.0400 mL 0.2001 mL 0.4001 mL 1.0003 mL
80 mM 0.0300 mL 0.1500 mL 0.3001 mL 0.7502 mL
100 mM 0.0240 mL 0.1200 mL 0.2401 mL 0.6002 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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ALS-I Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALS-I308818-13-5Biochemical Assay ReagentsenzymaticdigestionssolubilizehydrophobicproteinsInhibitorinhibitorinhibit

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