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  2. Primary Antibodies
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  4. MLH1 Antibody (YA703)

MLH1 Antibody (YA703)

Cat. No.: HY-P80753
COA User Guide for Antibodies

MLH1 Antibody (YA703) is a non-conjugated and Mouse origined monoclonal antibody about 85 kDa, targeting to MLH1 (4C1). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Monkey.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $100 In-stock
50 μL $270 In-stock
100 μL $430 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

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Description

MLH1 Antibody (YA703) is a non-conjugated and Mouse origined monoclonal antibody about 85 kDa, targeting to MLH1 (4C1). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Monkey.

Background

MLH1 (4C1): The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). [provided by RefSeq, Aug 2017]

Tag

Free

Gene ID

4292

Synonyms
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Molecular Weight

Predicted band size: 85 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human, Monkey

SwissProt ID

P40692

Dilution Ratio

WB: 1:500-1:1,000 ;IF: 1:50-1:200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to MLH1.AA range:381-483.

Documentation

MLH1 Antibody (YA703) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MLH1 Antibody (YA703)
Cat. No.:
HY-P80753
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