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  4. SMC1A Antibody (YA673)

SMC1A Antibody (YA673)

Cat. No.: HY-P80894
User Guide for Antibodies

SMC1A Antibody (YA673) is a non-conjugated and Mouse origined monoclonal antibody about 143 kDa, targeting to SMC1A (4C5). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Description

SMC1A Antibody (YA673) is a non-conjugated and Mouse origined monoclonal antibody about 143 kDa, targeting to SMC1A (4C5). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

Background

SMC1A (4C5): Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Tag

Free

Gene ID

8243

Synonyms
Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromoso
Molecular Weight

Predicted band size: 143 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cell Biology

Product Categories

Primary Antibody; Mouse Monoclonal Antibody

Clonality

Monoclonal

Host

Mouse

Reactivity

Human

SwissProt ID

Q14683

Dilution Ratio

WB: 1:500-1:1,000 ;IF: 1:50-1:200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG1

Sensitivity

Endogenous

Immunogen

Synthetic peptide corresponding to Human SMC1A.The exact sequence is proprietary to MCE.

Documentation

SMC1A Antibody (YA673) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SMC1A Antibody (YA673)
Cat. No.:
HY-P80894
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