Argininosuccinic acid disodium

Name: Argininosuccinic acid disodium
Brand: MedChemExpress
SKU: HY-113149A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113149A Purity: ≥96.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain.

For research use only. We do not sell to patients.

Argininosuccinic acid disodium Chemical Structure

CAS No. : 918149-29-8

Size	Price	Stock	Quantity
5 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Argininosuccinic acid disodium:

Argininosuccinic acid Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

334.24

Formula

C₁₀H₁₆N₄Na₂O₆

CAS No.

918149-29-8

Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCCNC(N[C@H](C(O[Na])=O)CC(O[Na])=O)=N)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (149.59 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9919 mL	14.9593 mL	29.9186 mL
5 mM	0.5984 mL	2.9919 mL	5.9837 mL
10 mM	0.2992 mL	1.4959 mL	2.9919 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥96.0%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244. [Content Brief]

[2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2023. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.9919 mL	14.9593 mL	29.9186 mL	74.7966 mL
	5 mM	0.5984 mL	2.9919 mL	5.9837 mL	14.9593 mL
	10 mM	0.2992 mL	1.4959 mL	2.9919 mL	7.4797 mL
	15 mM	0.1995 mL	0.9973 mL	1.9946 mL	4.9864 mL
	20 mM	0.1496 mL	0.7480 mL	1.4959 mL	3.7398 mL
	25 mM	0.1197 mL	0.5984 mL	1.1967 mL	2.9919 mL
	30 mM	0.0997 mL	0.4986 mL	0.9973 mL	2.4932 mL
	40 mM	0.0748 mL	0.3740 mL	0.7480 mL	1.8699 mL
	50 mM	0.0598 mL	0.2992 mL	0.5984 mL	1.4959 mL
	60 mM	0.0499 mL	0.2493 mL	0.4986 mL	1.2466 mL
	80 mM	0.0374 mL	0.1870 mL	0.3740 mL	0.9350 mL
	100 mM	0.0299 mL	0.1496 mL	0.2992 mL	0.7480 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.