2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Autophagy
  3. RAR/RXR Autophagy
  4. Bexarotene-d4

Bexarotene-d4  (Synonyms: LGD1069 d4)

Cat. No.: HY-14171S Purity: 99.11%
COA Handling Instructions

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Bexarotene-d4 is a deuterium labeled Bexarotene (LGD1069). Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma[1][2][3][4][5].

For research use only. We do not sell to patients.

Bexarotene-d<sub>4</sub> Chemical Structure

Bexarotene-d4 Chemical Structure

CAS No. : 2182068-00-2

Size Price Stock Quantity
1 mg USD 250 In-stock
5 mg USD 880 In-stock
10 mg USD 1540 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Bexarotene-d4:

Bexarotene-d4 Related Antibodies

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Description

Bexarotene-d4 is a deuterium labeled Bexarotene (LGD1069). Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma[1][2][3][4][5].

Molecular Weight

352.50

Formula

C24H24D4O2
CAS No.
Unlabeled CAS

153559-49-0
Appearance

Solid

Color

White to off-white

SMILES

CC1(C2=C(C(C)(CC1)C)C=C(C(C(C3=C([2H])C([2H])=C(C([2H])=C3[2H])C(O)=O)=C)=C2)C)C
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 20 mg/mL (56.74 mM)

DMSO : ≥ 10 mg/mL (28.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 0.5 mg/mL (1.42 mM)

DMF:PBS (pH 7.2)(1:3) : ≥ 0.25 mg/mL (0.71 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8369 mL 14.1844 mL 28.3688 mL
5 mM 0.5674 mL 2.8369 mL 5.6738 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / DMF 1 mM 2.8369 mL 14.1844 mL 28.3688 mL 70.9220 mL
DMSO / DMF 5 mM 0.5674 mL 2.8369 mL 5.6738 mL 14.1844 mL
10 mM 0.2837 mL 1.4184 mL 2.8369 mL 7.0922 mL
15 mM 0.1891 mL 0.9456 mL 1.8913 mL 4.7281 mL
20 mM 0.1418 mL 0.7092 mL 1.4184 mL 3.5461 mL
25 mM 0.1135 mL 0.5674 mL 1.1348 mL 2.8369 mL
DMF 30 mM 0.0946 mL 0.4728 mL 0.9456 mL 2.3641 mL
40 mM 0.0709 mL 0.3546 mL 0.7092 mL 1.7730 mL
50 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.4184 mL
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Bexarotene-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bexarotene-d42182068-00-2LGD1069 d4RAR/RXRAutophagyRetinoic acid receptorsRetinoid X receptorsT-celllymphomabreastcancerCTCLInhibitorinhibitorinhibit

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