DNA ligase 1

Definition:

DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination.

References:

[1]. Patrick Maffucci, et al. Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies. J Clin Invest. 2018 Dec 3;128(12):5489-5504. [Content Brief]

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