G-protein-signaling modulator 3

Definition:

Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins.

References:

[1]. Xiaoqing Cao, et al. Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha. J Biol Chem. 2004 Jun 25;279(26):27567-74. [Content Brief]

[2]. Randall J Kimple, et al. Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. Biochem J. 2004 Mar 15;378(Pt 3):801-8. [Content Brief]

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