Galectin-3-binding protein

Definition:

Promotes integrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.

References:

[1]. A Ullrich, et al. The secreted tumor-associated antigen 90K is a potent immune stimulator. J Biol Chem. 1994 Jul 15;269(28):18401-7. [Content Brief]

[2]. N Tinari, et al. Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation. Int J Cancer. 2001 Jan 15;91(2):167-72. [Content Brief]

[3]. T Sasaki, et al. Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin. EMBO J. 1998 Mar 16;17(6):1606-13. [Content Brief]

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