Kelch-like protein 8

Definition:

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.

References:

[1]. Seunghee Nam, et al. Control of rapsyn stability by the CUL-3-containing E3 ligase complex. J Biol Chem. 2009 Mar 20;284(12):8195-206. [Content Brief]

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