Peroxisomal leader peptide-processing protease

Definition:

Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.

References:

[1]. Kanji Okumoto, et al. Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrix. J Biol Chem. 2011 Dec 30;286(52):44367-79. [Content Brief]

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