Phosphatidylinositol 4-kinase alpha

Definition:

Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.

References:

[1]. Fubito Nakatsu, et al. PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. J Cell Biol. 2012 Dec 10;199(6):1003-16. [Content Brief]

[2]. T Gehrmann, et al. Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230. Biochim Biophys Acta. 1999 Mar 25;1437(3):341-56. [Content Brief]

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