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  2. Phosphodiesterase (PDE)

Phosphodiesterase (PDE)

Definition:

Phosphodiesterase (PDE) is key enzymes in the adenosine and guanosine cyclic nucleotides (cAMP and cGMP) signaling cascade, acts by breaking the phosphodiester bond. Phosphodiesterase (PDE) is a large family with multiple genes. The development of selective phosphodiesterase inhibitors will open up new ideas for many diseases research.

Biomedical Dictionary

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