Programmed cell death ligand 1 (PD-L1)

Definition:

Programmed cell death ligand 1 (PD-L1) is a ligand of Programmed death receptor 1 (PD-1). PD-L1 is expressed in several human tumor tissues, and is able to effectively inhibit the activation, proliferation and secretion of cytokines related to T cells, the immune response and to induce T-cell failure or even apoptosis upon binding to PD-1.

References:

[1]. Yang X, Liu J. Targeting PD-L1 (Programmed death-ligand 1) and inhibiting the expression of IGF2BP2 (Insulin-like growth factor 2 mRNA-binding protein 2) affect the proliferation and apoptosis of hypopharyngeal carcinoma cells. Bioengineered. 2021 Dec;12(1):7755-7764. [Content Brief]

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