Protein disulfide-isomerase A2

Definition:

Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.

References:

[1]. Xinmiao Fu, et al. Human pancreas-specific protein disulfide isomerase homolog (PDIp) is redox-regulated through formation of an inter-subunit disulfide bond. Arch Biochem Biophys. 2009 May 1;485(1):1-9. [Content Brief]

[2]. Xin-Miao Fu, et al. Human pancreas-specific protein disulfide isomerase homolog (PDIp) is an intracellular estrogen-binding protein that modulates estrogen levels and actions in target cells. J Steroid Biochem Mol Biol. 2009 May;115(1-2):20-9. [Content Brief]

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