Protein misato homolog 1

Definition:

Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.

References:

[1]. Masashi Kimura, et al. Human Misato regulates mitochondrial distribution and morphology. Exp Cell Res. 2007 Apr 15;313(7):1393-404. [Content Brief]

[2]. Alessia Nasca, et al. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia. Hum Mutat. 2017 Aug;38(8):970-977. [Content Brief]

[3]. Aniko Gal, et al. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans. EMBO Mol Med. 2017 Jul;9(7):967-984. [Content Brief]

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