Tetratricopeptide repeat protein 12

Definition:

Cytoplasmic protein that plays a role in the proper assembly of dynein arm complexes in motile cilia in both respiratory cells and sperm flagella.

References:

[1]. Lucie Thomas, et al. TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella. Am J Hum Genet. 2020 Feb 6;106(2):153-169. [Content Brief]

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