2. Biology Dictionary
  3. Trans-acting T-cell-specific transcription factor GATA-3

Trans-acting T-cell-specific transcription factor GATA-3

Definition:

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity).

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