Transcription factor ETV6

Definition:

Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.

References:

[1]. Michael Y Zhang, et al. Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy. Nat Genet. 2015 Feb;47(2):180-5. [Content Brief]

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