Transmembrane protein 177

Definition:

Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

References:

[1]. Isotta Lorenzi, et al. The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis. Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):323-333. [Content Brief]

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