Tripartite motif-containing protein 44

Definition:

May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17. Is a negative regulator of PAX6 expression.

References:

[1]. Xibo Zhang, et al. Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression. Hum Mutat. 2015 Dec;36(12):1164-7. [Content Brief]

[2]. Tomohiko Urano, et al. TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase. Biochem Biophys Res Commun. 2009 May 29;383(2):263-8. [Content Brief]

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