Zinc fingers and homeoboxes protein 3

Definition:

Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.

References:

[1]. Fumio Suehiro, et al. Impact of zinc fingers and homeoboxes 3 on the regulation of mesenchymal stem cell osteogenic differentiation. Stem Cells Dev. 2011 Sep;20(9):1539-47. [Content Brief]

[2]. Kazuya Yamada, et al. Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3. Biochem J. 2003 Jul 1;373(Pt 1):167-78. [Content Brief]

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