2. Others
  3. Isotope-Labeled Compounds
  4. CML-d3

CML-d3 is the deuterium labeled CML.

For research use only. We do not sell to patients.

CML-d<sub>3</sub> Chemical Structure

CML-d3 Chemical Structure

CAS No. : 2699607-49-1

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Based on 1 publication(s) in Google Scholar

Other Forms of CML-d3:

CML-d3 Related Antibodies

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Description

CML-d3 is the deuterium labeled CML.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CML-d3 Related Antibodies
Molecular Weight

207.24

Formula

C8H13D3N2O4
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

OC([C@](N)([2H])CCCC([2H])([2H])NCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

PBS (pH 7.2) : ≥ 10 mg/mL (48.25 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8253 mL 24.1266 mL 48.2532 mL
5 mM 0.9651 mL 4.8253 mL 9.6506 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
PBS (pH 7.2) 1 mM 4.8253 mL 24.1266 mL 48.2532 mL 120.6331 mL
5 mM 0.9651 mL 4.8253 mL 9.6506 mL 24.1266 mL
10 mM 0.4825 mL 2.4127 mL 4.8253 mL 12.0633 mL
15 mM 0.3217 mL 1.6084 mL 3.2169 mL 8.0422 mL
20 mM 0.2413 mL 1.2063 mL 2.4127 mL 6.0317 mL
25 mM 0.1930 mL 0.9651 mL 1.9301 mL 4.8253 mL
30 mM 0.1608 mL 0.8042 mL 1.6084 mL 4.0211 mL
40 mM 0.1206 mL 0.6032 mL 1.2063 mL 3.0158 mL
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CML-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CML-d32699607-49-1Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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