Cn2 toxin  (Synonyms: β-Mammal toxin Cn2)

Cn2 toxin is aβ- toxoins. Cn2 toxin can bind to the voltage sensing domain of voltage gated sodium channels (Na_v) ^[1].

7588.60

C₃₃₆H₄₉₆N₉₀O₉₆S₈

Lys-Glu-Gly-Tyr-Leu-Val-Asp-Lys-Asn-Thr-Gly-Cys-Lys-Tyr-Glu-Cys-Leu-Lys-Leu-Gly-Asp-Asn-Asp-Tyr-Cys-Leu-Arg-Glu-Cys-Lys-Gln-Gln-Tyr-Gly-Lys-Gly-Ala-Gly-Gly-Tyr-Cys-Tyr-Ala-Phe-Ala-Cys-Trp-Cys-Thr-His-Leu-Tyr-Glu-Gln-Ala-Ile-Val-Trp-Pro-Leu-Pro-Asn-Lys-Arg-Cys-Ser-NH2 (Disulfide bridge:Cys12-Cys65;Cys16-Cys41;Cys25-Cys46;Cys29-Cys48)

KEGYLVDKNTGCKYECLKLGDNDYCLRECKQQYGKGAGGYCYAFACWCTHLYEQAIVWPLPNKRCS-NH2 (Disulfide bridge:Cys12-Cys65;Cys16-Cys41;Cys25-Cys46;Cys29-Cys48)

O=C([C@@H](N)CCCCN)N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC(C(NC(C(NC(C(NC(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(NCC(NCC(N[C@H]1CC2=CC=C(O)C=C2)=O)=O)=O)C)=O)=O)CCCCN)=O)=O)CC3=CC=C(O)C=C3)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCCN)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5[C@H](C(N[C@H](C(N6[C@H](C(N[C@H](C(N[C@H](C(N[C@H]7CCCNC(N)=N)=O)CCCCN)=O)CC(N)=O)=O)CCC6)=O)CC(C)C)=O)CCC5)=O)CC8=CNC9=CC=CC=C89)=O)C(C)C)=O)[C@H](CC)C)=O)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC%10=CC=C(O)C=C%10)=O)CC(C)C)=O)CC%11=CNC=N%11)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CSSCC(NC%12=O)C(N[C@H]4CC%13=CNC%14=CC=CC=C%13%14)=O)=O)CC%15=CC=C(O)C=C%15)=O)CC(O)=O)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)CSSC[C@H](NC1=O)C(NC(C(NC(C(NC(C(NC%12C)=O)CC%16=CC=CC=C%16)=O)C)=O)CC%17=CC=C(O)C=C%17)=O)=O)CCC(O)=O)=O)CC%18=CC=C(O)C=C%18)=O)CCCCN)=O)CSSC[C@H](NC7=O)C(N[C@H](C(N)=O)CO)=O)=O)=O)[C@@H](C)O)=O)CC(N)=O)=O)CCCCN)=O)CC(O)=O)=O)C(C)C)=O)CC(C)C)=O)CC%19=CC=C(O)C=C%19)=O)=O)CCC(O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Chen R, et al. Conserved functional surface of antimammalian scorpion β-toxins. J Phys Chem B. 2012 Apr 26;116(16):4796-800.  [Content Brief]