1. Immunology/Inflammation Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  2. Glucocorticoid Receptor Endogenous Metabolite
  3. Cortisone-13C3

Cortisone-13C3 is the 13C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].

For research use only. We do not sell to patients.

Cortisone-<sup>13</sup>C<sub>3</sub> Chemical Structure

Cortisone-13C3 Chemical Structure

CAS No. : 2350278-95-2

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Solvent
100μg(275.16 μM * 1 mL in Methanol) USD 2150 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Cortisone-13C3 is the 13C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

363.42

Formula

C1813C3H28O5

CAS No.
Unlabeled CAS

53-06-5

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(CO)[C@@]1(O)CCC([C@]1(C)C2)C3CCC4=[13C][13C]([13C]C[C@]4(C)C3C2=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cortisone-13C3
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HY-17461S
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