1. Anti-infection Immunology/Inflammation GPCR/G Protein
  2. Fungal CXCR
  3. Corydalmine

Corydalmine  (Synonyms: L-Corydalmine; TLZ-16)

Cat. No.: HY-N2573
Handling Instructions

Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway.

For research use only. We do not sell to patients.

Corydalmine Chemical Structure

Corydalmine Chemical Structure

CAS No. : 30413-84-4

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Description

Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].

IC50 & Target[3]

CXCR2

 

In Vivo

Corydalmine (L-Corydalmine) is a potent analgesic agent, in cynomolgus monkey, beagle dog, rat and mouse liver microsomes[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

341.40

Formula

C20H23NO4

CAS No.
SMILES

OC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@]3([H])C2)=C1OC

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Corydalmine
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