2. GPCR/G Protein
  3. Oxytocin Receptor
  4. (d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin 

Cat. No.: HY-P2014
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(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior.

For research use only. We do not sell to patients.

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin Chemical Structure

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin Chemical Structure

CAS No. : 114056-26-7

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(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin Related Antibodies

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Description

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior[1].

IC50 & Target

Oxytocin[1]
In Vivo

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (50-1000 ng; Intra-MPOA; 1 μL) inhibits certain aspects of male sexual behavior in rats[1].
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (100 ng; i.c.v.; 1 μL) effectively suppresses hypoalgesia following copulatory behavior in male rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult Long–Evans/Blue-Spruce rats[1]
Dosage: 50 ng, 200 ng, and 1 μg
Administration: Intra-MPOA (medial preoptic area) injection, 1 μL
Result: Significantly increased intromission latency and anogenital investigation at 1 μg dose. Significantly decreased intromission ratio (2) at all doses.
Animal Model: Adult male and female Long-Evans rats (8 weeks old, 220–260 g BW)[2]
Dosage: 100 ng
Administration: Intracerebroventricular injection, 1 μL
Result: Was effective in reducing pain threshold heightened by copulatory behavior.
Molecular Weight

1154.40

Formula

C54H79N11O13S2
CAS No.
Unlabeled CAS

Sequence Shortening

XYITNC(Unk)PXY(Me)-NH2
SMILES

O=C([C@H]1N(C([C@@H](NC([C@H](CC(N)=O)NC([C@H]([C@H](O)C)NC(C([C@@H](C)CC)NC([C@H](CC2=CC=C(OC)C=C2)NC(C3)=O)=O)=O)=O)=O)CSSC43CCCCC4)=O)CCC1)N[C@@H](CCCN)C(N[C@@H](CC5=CC=C(O)C=C5)C(N)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin114056-26-7Oxytocin ReceptorOXTRoxytocinsexual behaviorInhibitorinhibitorinhibit

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