2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Dipyridamole-d20

Dipyridamole-d20 is the deuterium labeled Dipyridamole. Dipyridamole is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells[1][2][3].

For research use only. We do not sell to patients.

Dipyridamole-d<sub>20</sub> Chemical Structure

Dipyridamole-d20 Chemical Structure

CAS No. : 1189983-52-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Dipyridamole-d20:

Dipyridamole-d20 Related Antibodies

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Description

Dipyridamole-d20 is the deuterium labeled Dipyridamole. Dipyridamole is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dipyridamole-d20 Related Antibodies
Molecular Weight

524.75

Formula

C24H20D20N8O4
CAS No.
Unlabeled CAS

58-32-2
Appearance

Solid

Color

Light yellow to yellow

SMILES

N(CCO)(CCO)C1=NC2=C(C(=N1)N3C(C(C(C(C3([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])N=C(N(CCO)CCO)N=C2N4C(C(C(C(C4([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (95.28 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.67 mg/mL (1.28 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9057 mL 9.5283 mL 19.0567 mL
5 mM 0.3811 mL 1.9057 mL 3.8113 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (262 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.9057 mL 9.5283 mL 19.0567 mL 47.6417 mL
DMSO 5 mM 0.3811 mL 1.9057 mL 3.8113 mL 9.5283 mL
10 mM 0.1906 mL 0.9528 mL 1.9057 mL 4.7642 mL
15 mM 0.1270 mL 0.6352 mL 1.2704 mL 3.1761 mL
20 mM 0.0953 mL 0.4764 mL 0.9528 mL 2.3821 mL
25 mM 0.0762 mL 0.3811 mL 0.7623 mL 1.9057 mL
30 mM 0.0635 mL 0.3176 mL 0.6352 mL 1.5881 mL
40 mM 0.0476 mL 0.2382 mL 0.4764 mL 1.1910 mL
50 mM 0.0381 mL 0.1906 mL 0.3811 mL 0.9528 mL
60 mM 0.0318 mL 0.1588 mL 0.3176 mL 0.7940 mL
80 mM 0.0238 mL 0.1191 mL 0.2382 mL 0.5955 mL
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Dipyridamole-d20 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dipyridamole-d201189983-52-5Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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