2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. DL-Mevalonolactone-d7

DL-Mevalonolactone-d7  (Synonyms: (±)-Mevalonolactone-d7; Mevalolactone-d7)

Cat. No.: HY-107855S Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

DL-Mevalonolactone-d7 is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

For research use only. We do not sell to patients.

DL-Mevalonolactone-d<sub>7</sub> Chemical Structure

DL-Mevalonolactone-d7 Chemical Structure

CAS No. : 347840-19-1

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1 mg USD 250 In-stock
5 mg USD 800 In-stock
10 mg USD 1280 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of DL-Mevalonolactone-d7:

DL-Mevalonolactone-d7 Related Antibodies

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Description

DL-Mevalonolactone-d7 is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DL-Mevalonolactone-d7 Related Antibodies
Molecular Weight

137.18

Formula

C6H3D7O3
CAS No.
Unlabeled CAS

674-26-0
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC1(CC(OC([2H])([2H])C1([2H])[2H])=O)C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (728.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 50 mg/mL (364.48 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2897 mL 36.4485 mL 72.8969 mL
5 mM 1.4579 mL 7.2897 mL 14.5794 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 7.2897 mL 36.4485 mL 72.8969 mL 182.2423 mL
5 mM 1.4579 mL 7.2897 mL 14.5794 mL 36.4485 mL
10 mM 0.7290 mL 3.6448 mL 7.2897 mL 18.2242 mL
15 mM 0.4860 mL 2.4299 mL 4.8598 mL 12.1495 mL
20 mM 0.3645 mL 1.8224 mL 3.6448 mL 9.1121 mL
25 mM 0.2916 mL 1.4579 mL 2.9159 mL 7.2897 mL
30 mM 0.2430 mL 1.2149 mL 2.4299 mL 6.0747 mL
40 mM 0.1822 mL 0.9112 mL 1.8224 mL 4.5561 mL
50 mM 0.1458 mL 0.7290 mL 1.4579 mL 3.6448 mL
60 mM 0.1215 mL 0.6075 mL 1.2149 mL 3.0374 mL
80 mM 0.0911 mL 0.4556 mL 0.9112 mL 2.2780 mL
100 mM 0.0729 mL 0.3645 mL 0.7290 mL 1.8224 mL
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DL-Mevalonolactone-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-Mevalonolactone-d7347840-19-1(±)-Mevalonolactone-d7Mevalolactone-d7Endogenous MetaboliteInhibitorinhibitorinhibit

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