2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. Estradiol benzoate-d3

Estradiol benzoate-d3  (Synonyms: β-Estradiol 3-benzoate-d3; 17β-Estradiol 3-benzoate-d3)

Cat. No.: HY-B1192S Purity: ≥99.0%
COA Handling Instructions

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Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

For research use only. We do not sell to patients.

Estradiol benzoate-d<sub>3</sub> Chemical Structure

Estradiol benzoate-d3 Chemical Structure

CAS No. : 1192354-74-7

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5 mg USD 1200 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Estradiol benzoate-d3:

Estradiol benzoate-d3 Related Antibodies

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Description

Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Estradiol benzoate-d3 Related Antibodies
Molecular Weight

379.51

Formula

C25H25D3O3
CAS No.
Unlabeled Cas

50-50-0
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC([2H])([2H])[C@]2([2H])O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC(C5=CC=CC=C5)=O)C=C4CC3
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (263.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.26 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6350 mL 13.1749 mL 26.3498 mL
5 mM 0.5270 mL 2.6350 mL 5.2700 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6350 mL 13.1749 mL 26.3498 mL 65.8744 mL
5 mM 0.5270 mL 2.6350 mL 5.2700 mL 13.1749 mL
10 mM 0.2635 mL 1.3175 mL 2.6350 mL 6.5874 mL
15 mM 0.1757 mL 0.8783 mL 1.7567 mL 4.3916 mL
20 mM 0.1317 mL 0.6587 mL 1.3175 mL 3.2937 mL
25 mM 0.1054 mL 0.5270 mL 1.0540 mL 2.6350 mL
30 mM 0.0878 mL 0.4392 mL 0.8783 mL 2.1958 mL
40 mM 0.0659 mL 0.3294 mL 0.6587 mL 1.6469 mL
50 mM 0.0527 mL 0.2635 mL 0.5270 mL 1.3175 mL
60 mM 0.0439 mL 0.2196 mL 0.4392 mL 1.0979 mL
80 mM 0.0329 mL 0.1647 mL 0.3294 mL 0.8234 mL
100 mM 0.0263 mL 0.1317 mL 0.2635 mL 0.6587 mL
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Estradiol benzoate-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estradiol benzoate-d31192354-74-7β-Estradiol 3-benzoate-d317β-Estradiol 3-benzoate-d3Estrogen Receptor/ERRInhibitorinhibitorinhibit

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