FFN270 hydrochloride 

FFN270 hydrochloride, a fluorescent tracer of norepinephrine, is a fluorescent substrate of the norepinephrine and vesicular monoamine transporters. FFN270 hydrochloride exhibits two resolved absorption/excitation maxima depending on solvent pH (FFN270 ex: 320 nm or 365 nm, em: 475 nm) and can function as ratiometric fluorescent pH-sensors^[1].

FFN270 enables both an examination of noradrenergic microanatomy and an observation of synaptic activity in the cortex of intact neuronal circuits in vivo^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

259.66

C₁₁H₁₁ClFNO₃

2341841-05-0

Solid

White to off-white

O=C1C(CCN)=CC2=CC=C(O)C(F)=C2O1.[H]Cl

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Matthew Dunn, et al. Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo. Nat Commun. 2018 Jul 19;9(1):2838.  [Content Brief]