1. Metabolic Enzyme/Protease Apoptosis Anti-infection
  2. Angiotensin-converting Enzyme (ACE) Apoptosis HIV
  3. Icariside D2

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis .

For research use only. We do not sell to patients.

Icariside D2 Chemical Structure

Icariside D2 Chemical Structure

CAS No. : 38954-02-8

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Description

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2].

In Vitro

Icariside D2 3 induces apoptosis via alteration of expression of apoptosis-related proteins and decreases phosphorylation of AKT in HL-60 cells[1].
Icariside D2 exhibits anti-inflammatory and anti-HIV activity[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

300.30

Formula

C14H20O7

CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H](OC2=CC=C(CCO)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: ≥98.0%

References
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Icariside D2
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HY-N7450
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