1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Tryptophan-d3

L-Tryptophan-d3  (Synonyms: Tryptophan-d3; Tryptophane-d3)

Cat. No.: HY-N0623S9 Purity: ≥99.0%
COA Handling Instructions

L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

For research use only. We do not sell to patients.

L-Tryptophan-d<sub>3</sub> Chemical Structure

L-Tryptophan-d3 Chemical Structure

CAS No. : 133519-78-5

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1 mg USD 150 In-stock
5 mg USD 390 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Tryptophan-d3:

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Description

L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

207.24

Formula

C11H9D3N2O2

CAS No.
Unlabeled CAS

73-22-3

Appearance

Solid

Color

White to light brown

SMILES

OC([C@](N)([2H])C([2H])([2H])C1=CNC2=CC=CC=C12)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 7.69 mg/mL (37.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 5 mg/mL (24.13 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8253 mL 24.1266 mL 48.2532 mL
5 mM 0.9651 mL 4.8253 mL 9.6506 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 4.8253 mL 24.1266 mL 48.2532 mL 120.6331 mL
5 mM 0.9651 mL 4.8253 mL 9.6506 mL 24.1266 mL
10 mM 0.4825 mL 2.4127 mL 4.8253 mL 12.0633 mL
15 mM 0.3217 mL 1.6084 mL 3.2169 mL 8.0422 mL
20 mM 0.2413 mL 1.2063 mL 2.4127 mL 6.0317 mL
DMSO 25 mM 0.1930 mL 0.9651 mL 1.9301 mL 4.8253 mL
30 mM 0.1608 mL 0.8042 mL 1.6084 mL 4.0211 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-Tryptophan-d3
Cat. No.:
HY-N0623S9
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