2. Cytoskeleton
  3. Integrin
  4. LDV-FITC

LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity.

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LDV-FITC Chemical Structure

LDV-FITC Chemical Structure

CAS No. : 1207610-07-8

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Other Forms of LDV-FITC:

LDV-FITC Related Antibodies

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Description

LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity[1][2].

IC50 & Target

α4β1 integrin[1]
Molecular Weight

1368.51

Formula

C69H81N11O17S
CAS No.
Unlabeled CAS

Appearance

Solid

Color

Light yellow to yellow

Sequence

{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-Leu-Asp-Val-Pro-Ala-Ala-{Lys(FITC)}
Sequence Shortening

{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-LDVPAA-{Lys(FITC)}
SMILES

O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)=O)=O)CC(O)=O)=O)C(C)C)=O)=O)C)=O)C)=O)CCCCNC(NC4=CC5=C(C=C4)C6(OC5=O)C7=C(C=C(C=C7)O)OC8=C6C=CC(O)=C8)=S)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (73.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7307 mL 3.6536 mL 7.3072 mL
5 mM 0.1461 mL 0.7307 mL 1.4614 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7307 mL 3.6536 mL 7.3072 mL 18.2680 mL
5 mM 0.1461 mL 0.7307 mL 1.4614 mL 3.6536 mL
10 mM 0.0731 mL 0.3654 mL 0.7307 mL 1.8268 mL
15 mM 0.0487 mL 0.2436 mL 0.4871 mL 1.2179 mL
20 mM 0.0365 mL 0.1827 mL 0.3654 mL 0.9134 mL
25 mM 0.0292 mL 0.1461 mL 0.2923 mL 0.7307 mL
30 mM 0.0244 mL 0.1218 mL 0.2436 mL 0.6089 mL
40 mM 0.0183 mL 0.0913 mL 0.1827 mL 0.4567 mL
50 mM 0.0146 mL 0.0731 mL 0.1461 mL 0.3654 mL
60 mM 0.0122 mL 0.0609 mL 0.1218 mL 0.3045 mL
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LDV-FITC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDV-FITC1207610-07-8Integrinα4β1fluorescent peptideInhibitorinhibitorinhibit

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